Traveler's Diarrhea

Azithromycin (Traveler's Diarrhea)

Oral tablet · 1 treatment course

Azithromycin is a broad-spectrum antibiotic and the CDC's first-line recommendation for traveler's diarrhea in South and Southeast Asia, where fluoroquinolone resistance is prevalent. Through Wandr Health, a treatment course is available from $89 with no appointment needed.

Overview

Traveler's diarrhea affects 30–70% of international travelers (CDC). Azithromycin targets the most common bacterial causes — Campylobacter, enterotoxigenic E. coli (ETEC), and Shigella — and is the CDC's preferred first-line option for South and Southeast Asia, where fluoroquinolone resistance is high.

Typically taken as a single 1,000 mg dose or 500 mg daily for 3 days. The CDC recommends self-treatment when diarrhea is incapacitating or accompanied by fever or bloody stools. Having a course on hand lets you begin treatment immediately.

Sources: CDC Yellow Book 2026; FDA prescribing information

Wandr Health vs. a traditional travel clinic

Wandr Health
Travel Clinic
Provider visit$89+$200+
Your timeUnder 10 minutesHours in a waiting room
AppointmentNone neededRequired
Follow-upUnlimited messagingNew appointment

Other travel medications

When travelers use this

  • Trips to South and Southeast Asia where fluoroquinolone resistance is common
  • Travelers who need a broad-spectrum option effective against Campylobacter
  • Those with fluoroquinolone allergies or contraindications
  • Backpackers and long-term travelers in high-risk regions like India and Nepal

Compare with Ciprofloxacin

Ciprofloxacin is the CDC's preferred option for most destinations outside South and Southeast Asia where fluoroquinolone resistance is low.

View Ciprofloxacin→

Related guides

Antibiotic stewardship

Wandr Health follows CDC guidelines for responsible antibiotic prescribing. All antibiotic prescriptions are reviewed by a licensed provider who evaluates appropriateness based on your destination and health profile.

Read our stewardship policy →

Frequently asked questions

Medical disclaimer
This page is for educational and informational purposes only and does not constitute medical advice. All treatment decisions are made by a licensed provider based on your individual health profile.
$89
Provider visit · Rx sent to your pharmacy
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Answer a few health questions. A licensed provider reviews and recommends treatment.
✓Licensed provider review included
✓Same-day pharmacy pickup
✓HSA/FSA eligible
✓Unlimited provider messaging
How it works
1
Answer a few questions about your trip
2
A provider reviews and recommends treatment
3
If prescribed, it's sent to a pharmacy near you
Questions?
Our care team can help with travel medication questions.
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Medically reviewed by the Wandr Health Medical Team · Last updated March 30, 2026
Same-day reviewFully onlineHIPAA compliant
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