Table Mountain rising over Cape Town with the Atlantic coastline of the Western Cape in the foreground
Travel health guide

South Africa

Africa (Southern Africa)Grade C (Elevated Risk)Risk score 67

South Africa is a diverse and breathtaking country known for its dramatic landscapes, wildlife safaris, vibrant cities, and rich cultural heritage. From the beaches of Cape Town and the Garden Route to Kruger National Park and Johannesburg’s urban energy, it...

  • CDC-aligned guidance
  • Licensed in all 50 states
  • HSA / FSA eligible
Safety grade
C (Elevated Risk)
Risk score
67 / 100
Region
Africa (Southern Africa)
Last updated
May 28, 2026

About South Africa

South Africa is a diverse and breathtaking country known for its dramatic landscapes, wildlife safaris, vibrant cities, and rich cultural heritage. From the beaches of Cape Town and the Garden Route to Kruger National Park and Johannesburg’s urban energy, it offers a dynamic mix of adventure, nature, and history.

Wandr's recommendations

  • Health considerations in South Africa vary by region.

  • While major cities offer good medical care, rural areas may have limited access.

  • The CDC recommends routine vaccinations, along with hepatitis A/B, typhoid, and rabies for some travelers.

  • Malaria is present in certain northeastern areas, particularly near Kruger, so mosquito precautions and chemoprophylaxis may be needed.

  • Tap water is generally safe in urban areas but bottled water is preferred in rural settings.

  • Travelers should come prepared for both outdoor exposure and urban health considerations.

US Centers for Disease Control and PreventionBased on data from the U.S. Centers for Disease Control and Prevention (CDC)
Common questions

Travel health FAQ

Wandr currently assigns South Africa a safety grade of C (Elevated Risk) and a risk score of 67/100. Grades summarize destination-specific risk across vaccine-preventable disease, common medication needs, altitude, climate, and outbreak alerts. Scores are derived from CDC, WHO, and US State Department guidance and updated regularly. Use the grade as a starting point — your personal plan still depends on your itinerary, health history, and length of stay.

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