South Africa

Africa (Southern Africa)
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About

South Africa

South Africa is a diverse and breathtaking country known for its dramatic landscapes, wildlife safaris, vibrant cities, and rich cultural heritage. From the beaches of Cape Town and the Garden Route to Kruger National Park and Johannesburg’s urban energy, it offers a dynamic mix of adventure, nature, and history.

Last Updated:

July 1, 2025

General Recommendations

Azithromycin / Ciprofloxacin - Traveler's Diarrhea

Ondansetron - Nausea & Vomiting

Meclizine - Motion Sickness

Hydroxyzine - Jet Lag / Traveler's Anxiety

Order them all with our comprehensive travel package, which includes all medications and country specific medications if required.

What is our Wandr Safety Rating?

Our safety grade combines CDC guidance, healthcare access, travel risks, and regional stability to help you prepare confidently. Updated regularly to reflect current conditions.

A (90–100): Very safe — Excellent healthcare and low travel risks
B (75–89): Safe — Minor precautions recommended
C (60–74): Moderate risk — Limited access or regional health concerns
D (40–59): Higher risk — Caution advised due to instability or health gaps
F (0–39): Not recommended — Major safety or medical concerns

Wandr Safety Rating:

C (Elevated Risk)

67/100

Health considerations in South Africa vary by region. While major cities offer good medical care, rural areas may have limited access. The CDC recommends routine vaccinations, along with hepatitis A/B, typhoid, and rabies for some travelers. Malaria is present in certain northeastern areas, particularly near Kruger, so mosquito precautions and chemoprophylaxis may be needed. Tap water is generally safe in urban areas but bottled water is preferred in rural settings. Travelers should come prepared for both outdoor exposure and urban health considerations.

CDC Recommendations

CDC Travel Information for South Africa

For the best experience, please view the CDC travel information directly on their website:

Go to CDC Travel Information for South Africa
Disclaimer: This page is intended as a general reference for travelers and does not replace personalized medical consultation. While Wandr provides medical guidance, country-specific risks may change. We update this information as frequently as possible, but travelers should also consult official government and health sources before departure.